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. 2018 Oct 8;10(10):1460. doi: 10.3390/nu10101460

Table 5.

Lipoprotein particle size following supplementation with 0–1 g/day n-3 LCPUFA from HiDHA™ tuna oil (values median (25th percentile, 75th percentile); n = 29).

0 g/day (n = 12)
0 weeks
0 g/day (n = 12)
8 weeks
0.35 g/day (n = 15)
0 weeks
0.35 g/day (n = 15)
8 weeks
0.7 g/day (n = 13)
0 weeks
0.7 g/day (n = 13)
8 weeks
1 g/day (n = 13)
0 weeks
1 g/day (n = 13)
8 weeks
Dose Effect (R2, p Value)
LDL Radius (nm) 10.9 (10.8, 11.0) 10.9 (10.7, 10.9) 11.0 (10.4, 11.1) 10.9 (10.4, 11.1) 10.9 (10.6, 11.1) 10.7 (10.5, 11.0) 10.9 (10.7, 11.0) 10.8 (10.8, 11.3) p = 0.15
% HDL2b 37 (32, 43) 33 (31, 44) 35 (16, 38) 35 (23, 38) 41 (28, 49) 46 (38, 50) 32 (28, 47) 42 (27, 52) R2 = 0.05, p = 0.04
% HDL2a 30 (27, 33) 28 (26, 37) 24 (22, 31) 25 (22, 31) 26 (21, 35) 26 (21, 32) 31 (22, 33) 31 (24, 33) p = 0.22
% HDL3a 19 (15, 23) 20 (15, 23) 20 (18, 29) 19 (17, 27) 19 (15, 25) 18 (14, 22) 18 (16, 20) 17 (13, 19) p = 0.24
% HDL3b 12 (7, 14) 11 (7, 16) 13 (10, 20) 13 (10, 18) 11 (7, 14) 9 (2, 12) 17 (11, 18) 9 (8, 19) R2 = 0.02, p = 0.07
% HDL3c 0.8 (0.0, 3.3) 0.3 (0.0, 3.9) 6.0 (0.6, 11.5) 6.1 (0.0, 12.5) 1.2 (0.0, 8.2) 1.9 (0.0, 8.2) 1.2 (0.6, 3.0) 0.6 (0.0, 2.1) p = 0.10

Abbreviations: LDL: low density lipoprotein; HDL: high density lipoprotein.