Table 2.
Effects of climb training (Trained) and/or resveratrol (RES) on biochemical assessments of serum at the end of the experiment.
| F Values for Two-Way ANOVA | |||||||
|---|---|---|---|---|---|---|---|
| Parameter | Sed + Vehicle | Sed + RES | Trained + Vehicle | Trained + RES | Main Effect of RES | Main Effect of Climb | Interaction (RES × Climb) |
| AST (U/L) | 129 ± 12 | 149 ± 22 | 116 ± 8 | 174 ± 37 | 3 | 0.07 | 0.68 |
| ALT (U/L) | 44 ± 3 a | 78 ± 12 b | 50 ± 5 a,b | 77 ± 17 b | 7.9 * | 0.06 | 0.1 |
| TG (mg/dL) | 114 ± 5 | 118 ± 9 | 124 ± 12 | 125 ± 9 | 0.06 | 0.81 | 0.02 |
| CK (U/L) | 400 ± 48 | 384 ± 83 | 360 ± 36 | 349 ± 61 | 0.05 | 0.4 | 0 |
| LDH (U/L) | 565 ± 46 | 672 ± 78 | 547 ± 28 | 634 ± 59 | 3.07 | 0.26 | 0.03 |
| BUN (mg/dL) | 24.5 ± 0.6 | 25.4 ± 1.1 | 25.8 ± 0.6 | 26.5 ± 1.3 | 0.64 | 1.5 | 0.01 |
| CREA (mg/dL) | 0.4 ± 0.01 | 0.4 ± 0.01 | 0.4 ± 0.01 | 0.4 ± 0.01 | 0 | 0 | 2 |
| UA (mg/dL) | 1.83 ± 0.14 a | 2.91 ± 0.31 b | 3.05 ± 0.39 b,c | 3.90 ± 0.40 c | 8.79 * | 11.53 * | 0.12 |
| ALB (g/dL) | 2.7 ± 0.1 | 2.7 ± 0.1 | 2.8 ± 0.1 | 2.8 ± 0.1 | 0.66 | 0.27 | 0.14 |
| TP (g/dL) | 5.4 ± 0.1 | 5.4 ± 0.1 | 5.5 ± 0.1 | 5.4 ± 0.1 | 0.67 | 0.05 | 0.12 |
| GLU | 148 ± 8 | 142 ± 10 | 157 ± 10 | 143 ± 6 | 1.34 | 0.28 | 0.25 |
Values are the mean ± SEM for n = 10 mice in each group. Values in the same line with different superscripts letters (a, b, c) differ significantly; *: P < 0.05 by two-way analysis of variance (ANOVA). Sed and Trained refer to the sedentary and climbing intervention, respectively. AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALB, albumin; LDH, lactate dehydrogenase; TP, total protein; BUN, blood urea nitrogen; CREA, creatine; UA, uric acid; TG, triacylglycerol; GLU, glucose.