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CMS-2 inhibits migration of melanoma and melanocyte cell line. Cell migration was evaluated by the scratch assay 0, 8, 24 and 48 h of CMS-2 treatment (2.5–10 μg/mL). Representative images and quantification of the closed area for: B16-F10 (A); and Melan-a (B). ** p < 0.01 and *** p < 0.001, Analysis of variance, Bonferroni post-test. The positive control was 5% fetal bovine serum (FBS) and the negative control was 0% FBS. The images were taken with 4× magnification.
