Table 2.
Gene ontology analysis.
| Pathways | Sample Frequency (n) | p-Value |
|---|---|---|
| Healthy against lesional condition | ||
| Keratinization (GO: 0031424) | 4 | 3.625 × 10−4 |
| Isoprenoid metabolic process (GO: 0006720) | 5 | 5.922 × 10−4 |
| Retinoid metabolic process (GO: 0001523) | 4 | 2.321 × 10−3 |
| Diterpenoid metabolic process (GO: 0016101) | 4 | 3.077 × 10−3 |
| Biological process (GO: 0008150) | 50 | 4.007 × 10−3 |
| Keratinocyte differentiation (GO: 0030216) | 4 | 5.312 × 10−3 |
| Non-lesional against lesional condition | ||
| Skin development (GO: 0043588) | 13 | 1.151 × 10−11 |
| Keratinization (GO: 0031424) | 5 | 7.952 × 10−6 |
| Epidermis development (GO: 0008544) | 8 | 1.088 × 10−5 |
| Single-organism developmental process (GO: 0044767) | 27 | 2.897 × 10−5 |
| Organ development (GO: 0048513) | 20 | 2.984 × 10−5 |
| Developmental process (GO: 0032502) | 27 | 3.619 × 10−5 |