Table 2.

Pairwise comparisons of 1-MT vs. MYR and of LPS vs. NaCl in peripheral and brain tissues using Tukey–Kramer test.

	1-MT LSM	MYR LSM	SE	p Value	LPS LSM	NaCl LSM	SE	p Value
TRP (nmol/g protein)
Amygdala	1094	1067	88	0.83	892	1269	88	<0.01
Prefrontal cortex	563	416	29	<0.001	477	502	29	0.47
Adrenal gland	1062	855	46	<0.001	926	992	46	0.22
Muscle	484	385	19	<0.001	397	472	18	<0.01
Lung	489	393	32	<0.05	396	486	31	<0.05
Liver	715	619	33	<0.05	597	737	32	<0.01
Heart	685	569	41	<0.05	569	685	39	<0.05
Hippocampus	224	178	11	<0.01	189	213	11	0.12
Hypothalamus	79	67	4	<0.05	70	76	4	0.19
Spleen	746	636	31	<0.05	687	696	32	0.84
Kidney	1337	1249	42	0.10	1211	1375	42	<0.01
Thyroid gland	459	495	30	0.31	469	485	29	0.67
KYN (nmol/g protein)
Liver	604.86	590.86	35.62	0.64	586.74	608.98	34.99	0.48
Lung	123.16	156.84	21.97	0.29	180.15	99.85	22.08	<0.05
Spleen	12.83	11.45	1.79	0.58	18.28	6.00	1.80	<0.001
Hippocampus	19.69	19.74	1.78	0.98	19.50	19.93	1.78	0.87
KYNA (nmol/g protein)
Lung	3.83	2.4	0.34	<0.01	3.34	2.90	0.005	0.30
Kidney	0.71	0.57	0.05	<0.05	0.65	0.63	0.05	0.80
Liver	5.84	4.75	0.46	0.06	5.64	4.95	0.47	0.23

Results of TRP, KYN and KYNA concentrations are presented as LS-means (LSM) and SE. 1-MT: n = 24; MYR: n = 23; LPS: n = 23; NaCl: n = 24.