Table 3.
Correlation analysis of serum levels of BDNF and clinical variables.
| Parameters | GDS-SF (n = 26) | K-MMSE (n = 38) | NIHSS (n = 38) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| T0 | T1 | T2 | T0 | T1 | T2 | T0 | T1 | T2 | ||
| Mature BDNF (ng/mL) |
T0 | 0.480 * | - | - | 0.043 | - | - | 0.045 | - | - |
| (0.013) | (0.800) | (0.788) | ||||||||
| T1 | - | 0.477 * | - | - | −0.104 | - | - | 0.186 | - | |
| (0.014) | (0.541) | (0.263) | ||||||||
| T2 | - | - | 0.480 * | - | - | −0.180 | - | - | 0.194 | |
| (0.013) | (0.280) | (0.243) | ||||||||
| ProBDNF (ng/mL) |
T0 | 0.006 | - | - | −0.168 | - | - | 0.126 | - | - |
| (0.977) | (0.313) | (0.452) | ||||||||
| T1 | - | 0.141 | - | - | −0.111 | - | 0.117 | - | ||
| (0.492) | (0.513) | (0.483) | ||||||||
| T2 | - | - | 0.373 | - | - | 0.048 | - | - | 0.024 | |
| (0.060) | (0.775) | (0.888) | ||||||||
| MMP-9 (ng/mL) |
T0 | 0.079 | - | - | −0.394 * | - | - | 0.495 * | - | - |
| (0.700) | (0.014) | (0.002) | ||||||||
| T1 | - | 0.312 | - | - | −0.191 | - | 0.355 * | - | ||
| (0.120) | (0.256) | (0.029) | ||||||||
| T2 | - | - | 0.093 | - | −0.207 | - | - | 0.147 | ||
| (0.651) | (0.213) | (0.379) | ||||||||
Values are presented as correlation coefficient (p-value). GDS-SF, Geriatric Depression Scale-Short Form; K-MMSE, Korean Mini-Mental Status Examination; NIHSS, National Institutes of Health Stroke Scale; BDNF, brain-derived neurotrophic factor; MMP-9, matrix metalloproteinase-9. * p < 0.05.