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(a–d) Two alternative conformations of the HCMV (a,c) and HSV-1 (b,d) Hexagons observed during the MD (molecular dynamics) simulations. Each chain is coloured individually. Inter-subunit distances between E282R225 (HCMV) or E302K262 (HSV-1) of OIF I are highlighted with pink bars. For three of these six OIF I interactions, the time course is displayed in panels (e,f): HCMV (e), and HSV-1 (f).
