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. 2018 Sep 27;19(10):2939. doi: 10.3390/ijms19102939

Figure 3.

Figure 3

Chemical exposure induced differential alterations in NT and NTR expression in the MOE of TRPM5-GFP and Skn-1a−/− mice. Real-time qPCR analysis and comparison of the expression of NTs and NTRs in the MOE of mice exposed to either vehicle (water) or a chemical mixture for 2 weeks. Gapdh was detected as the reference gene. (A) Relative expression levels of NTs and NTRs in TRPM5-GFP mice. No significant differences in the expression levels of NTs or NTRs were observed in the MOE of chemical-exposed mice compared to water-exposed mice except for p75NTR expression, which decreased significantly in the MOE of the chemical-exposed group. (B) Relative expression levels of NTs and NTRs in Skn-1a−/− mice. The expression of p75NTR in the MOE of the chemical-exposed group was significantly higher than in the vehicle-exposed group. * p < 0.05, two-tailed independent t test, n = 6. Bar graphs represent the mean ± SD.