Table 1.
Effect of luteolin treatment for 16 weeks on body and organ weights, and plasma and hepatic FFA levels in C57BL/6J mice fed the high-fat diet.
| ND | HFD | LU | |
|---|---|---|---|
| Initial Body Weight (g) | 19.33 ± 0.25 | 19.33 ± 0.32 | 19.33 ± 0.29 |
| Final Body Weight (g) | 30.32 ± 0.78 | 42.17 ± 0.89 *** | 37.48 ± 0.79 §§§ |
| Body Weight Gain (g/weeks) | 0.70 ± 0.07 | 1.47 ± 0.07 *** | 1.12 ± 0.07 §§§ |
| Liver (g/100 g BW) | 3.54 ± 0.13 | 6.57 ± 0.20 *** | 5.87 ± 0.30 |
| Visceral WAT (g/100 g BW) | 5.83 ± 0.31 | 9.63 ± 0.19 *** | 7.33 ± 0.24 §§§ |
| Subcutaneous WAT (g/100 g BW) | 1.62 ± 0.10 | 3.65 ± 0.10 *** | 2.51 ± 0.05 §§§ |
| Total WAT (g/100 g BW) | 8.62 ± 0.52 | 15.31 ± 0.27 *** | 11.68 ± 0.20 §§§ |
| Plasma FFA (mmol/L) | 1.13 ± 0.07 | 1.43 ± 0.04 ** | 1.15 ± 0.02 §§§ |
| Hepatic FFA (mEq/g liver) | 0.014 ± 0.001 | 0.028 ± 0.001 *** | 0.020 ± 0.001 §§§ |
Data are shown as means ± SEM. ND vs HFD: * p < 0.05, ** p < 0.01, *** p < 0.001. HFD vs LU: § p < 0.05, §§ p < 0.01, §§§ p < 0.001. BW, body weight; WAT, white adipose tissue; FFA, free fatty acid, ND, normal diet, HFD, high-fat diet, LU, Luteolin.