Table 1.
Morphological measurements and biochemical parameters from Sprague-Dawley rats with different diets. HDL, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; AST, aspartate aminotransferase; ALT, alanine aminotransferase.
| Parameter | STD | HFHS | HFHS + ω3 | |||
|---|---|---|---|---|---|---|
| Mean | s.d. c | Mean | s.d. c | Mean | s.d. c | |
| Body weight after 24 weeks | 539.6 | 49.4 | 568.3 * | 24.3 | 579.9 * | 35.7 |
| Length | 25.7 | 0.4 | 26.5 | 0.6 | 26.4 | 0.4 |
| Perigonadal Adipose Tissue | 9.0 | 3.2 | 13.1 | 3.9 | 13.3 | 4.4 |
| Adiposity index (%) a | 1.7 | 2.3 ** | 2.3 ** | |||
| Hepatosomatic index (%) b | 0.50 | 0.44 | 0.43 | |||
| Liver weight | 2.7 | 2.5 | 2.5 | |||
| Liver fat content | 7.01 | 0.61 | 6.64 | 0.79 | 6.55 | 0.70 |
| Triglycerides (mmol/L) | 0.69 | 0.20 | 0.52 | 0.26 | 0.59 | 0.23 |
| Cholesterol (mmol/L) | 3.61 | 0.38 | 2.90 | 0.50 | 2.55 | 0.42 |
| HDL (mmol/L) | 1.15 | 0.12 | 0.94 | 0.16 | 0.85 | 0.12 |
| LDL (mmol/L) | 0.43 | 0.11 | 0.39 | 0.09 | 0.32 | 0.07 |
| Plasmatic Insulin ng/mL | 0.95 | 0.6 | 2.0 * | 0.25 | 2.1 * | 0.40 |
| Plasmatic Glucose mg/mL | 65 | 2 | 66 | 1.5 | 64 | 2 |
| AST (U/L) | 70.19 | 21.91 | 57.12 * | 10.74 | 53.58 * | 10.15 |
| ALT (U/L) | 27.09 | 8.24 | 19.03 * | 3.88 | 22.84 | 4.18 |
| AST/ALT | 2.64 | 0.52 | 3.14 | 0.92 | 2.37 | 0.29 |
| ALT/AST | 0.39 | 0.08 | 0.35 | 0.12 | 0.43 | 0.05 |
a Adiposity index: (total abdominal fat × 100)/body weight; b Hepatosomatic index: (liver weight × 100)/body weight; c s.d., standard deviation; * Pb.05 vs. standard (STD) control group; ** Pb.01 vs. STD control group.