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. 2018 Oct 1;37(21):e99278. doi: 10.15252/embj.201899278

Figure EV3. Deletion of NMD4 and EBS1 stabilize a set of transcripts that is also stabilized in the absence of UPF1 .

Figure EV3

  • A–E
    Examples of NMD substrates sequencing profiles in WT, upf1∆, nmd4∆, ebs1∆ and nmd4∆/ebs1∆ experiments. NMD substrates belong to different classes, intron containing (RPL28; A and B, different scaling to show intron signal), uORF (DAL7, DAL2; C and D) and non‐coding RNA (SUT439; E). Profiles were normalized using the samples median counts.
  • F
    Scatter plot of transcript log2 fold change in upf1∆ against ebs1∆. The dashed line represents the limit over which RNA was considered as stabilized, with a log2 value of 0.5 (1.4 fold change).