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. 2018 Sep 28;10(10):1381. doi: 10.3390/nu10101381

Figure 1.

Figure 1

Effects of DKB114 on serum and urinary uric acid levels in normal rats and rats with PO-induced hyperuricemia. (A) Serum uric acid levels in normal rats. (B) and (C) Serum uric acid levels in rats with PO-induced hyperuricemia (Exp1 and 2), and (D) urinary uric acid levels in rats with PO-induced hyperuricemia (Exp2). Blood samples were collected 2h after PO injection and DKB114 treatment. Urine samples were collected using metabolic cages at indicated times after PO injection and DKB114 treatment. NC, normal control group; PO, potassium oxonate-induced hyperuricemia group; DKB114, a mixture of ethanol extracts of Chrysanthemum indicum Linne flower (CF) and Cinnamomum cassia (L.) J. Presl bark (CB) in a 1:2 ratio; AP 10, 10 mg/kg allopurinol; Ben 50: 50 mg/kg benzbromarone. Data are expressed as the mean ± SEM (n = 6–10). # p < 0.05, ### p < 0.005, and #### p < 0.001 vs. the NC group; * p < 0.05, ** p < 0.01, *** p < 0.005, and **** p < 0.001 vs. the PO group.