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. 2018 Sep 28;10(10):1381. doi: 10.3390/nu10101381

Figure 2.

Figure 2

Effects of DKB114 on XOD activity in vitro/in vivo and hepatic uric acid levels. (A) In vitro xanthine oxidase (XOD) inhibitory activity, (B) liver XOD activity, and (C) liver uric acid levels. Liver tissue for analysis of XOD activity and uric acid levels was harvested in Exp1. NC, normal control group; PO, potassium oxonate-induced hyperuricemia group; DKB114, a mixture of ethanol extracts of Chrysanthemum indicum Linne flower (CF) and Cinnamomum cassia (L.) J. Presl bark (CB) in a 1:2 ratio; AP 10: 10 mg/kg allopurinol. Data are expressed as the mean± SEM (n = 4) and representative of three independent experiments in vitro XOD activity and in vivo data are expressed as the mean ± SEM (n = 6). # p < 0.05 vs. the NC group; * p < 0.05, ** p < 0.01, and *** p < 0.005 vs. the PO group.