Table 1.
Effects of hesperidin and captopril on blood pressure and heart rate in anesthetized rats.
| Parameters | Control | l-NAME | l-NAME + H15 | l-NAME + H30 | l-NAME + Cap |
|---|---|---|---|---|---|
| SP (mmHg) | 120.92 ± 2.27 | 205.88 ± 3.19 * | 179.38 ± 16.51 *,# | 154.07 ± 4.88 *,#,$ | 140.14 ± 7.06 #,$ |
| DP (mmHg) | 72.68 ± 3.31 | 141.65 ± 5.73 * | 114.13 ± 16.57 *,# | 86.89 ± 5.74 *,#,$ | 91.48 ± 7.36 #,$ |
| MAP (mmHg) | 88.76 ± 2.47 | 161.41 ± 4.01 * | 135.88 ± 16.00 *,# | 109.28 ± 5.39 *,#,$ | 107.70 ± 6.27 #,$ |
| HR (beat/min) | 367.86 ± 11.90 | 419.30 ± 11.96 * | 391.93 ± 14.35 | 351.44 ± 13.47 #,$ | 384.28 ± 17.31 |
SP: systolic blood pressure; DP: diastolic blood pressure; MAP: mean arterial pressure; HR: heart rate. Values are mean ± S.E.M (n = 7–8/group), * p < 0.05 vs. control, # p < 0.05 vs. l-NAME, $ p < 0.05 vs. l-NAME + H15.