Figure 6.

Inhibition of PI3K/Akt/mTOR pathway in SGC-7901 cells by LP1. (A) The expression levels of p-mTOR, mTOR, p-Akt, Akt and PI3K proteins were analyzed by western blotting assay. SGC-7901 cells were treated with various concentrations of LP1 (0, 30, 60, 90 µg/mL) for 48 h, GAPDH was used as an internal control. Data are expressed as means ± SD of three independent experiments. (A1–A3) Western blots were quantified by densitometry, results are expressed as mean ± SD and * p < 0.05, ** p < 0.01) of three independent experiments.