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. 2018 Oct 22;16(10):397. doi: 10.3390/md16100397

Table 1.

In vivo bioaccessibility of fucoxanthin in rodents: Maxima concentration determined in different tissues and plasma.

Dose Plasma Liver Adipose Tissue Ref.
F 7 FxOH AxA F FxOH AxA F FxOH AxA
1.5 nmol FxOH s.d. 1 i.v. 2 29.1 pmol/mL 17.2 pmol/mL 108.9 pmol/g 18.2 pmol/g [29]
160 nmol F
s.d. i.g. 3
132 nmol/L 230 nmol/L 584 nmol/g 190 nmol/g 39 nmol/g 84 nmol/g [36]
160 nmol/d F
7 d i.g.
45 nmol/L 82 nmol/L 15 nmol/g 83 nmol/g 40 nmol/g 23.1 nmol/g 60 nmol/g 97 nmol/g [36]
40 nmol F
s.d. i.s. 4
0.4 nmol/L [28]
0.05% F
5 w diet 5
78.1 µg/g protein 64.7 µg/g protein [38]
0.128 mmol/d F
14 d diet 5
0.34 µmol/L 0.95 µmol/L 0.85 µmol/kg 0.96 µmol/kg 2.14 µmol/kg 7.85 µmol/kg [34]
3.1 µmol F
s.d. d.i. 6
0.33 µmol 8 [39]
3.2 µmol FxOH
s.d. d.i.
0.44 µmol 8 [39]
2 mg/kg F
s.d. i.v.
14,000 µg/L 598.2 µg/L [40]
65 mg/kg F
s.d. i.g.
29.1 µg/L 263.3 µg/L [40]
7 mg/kg F
s.d.
18.8 nmol/L 68.6 nmol/L [41]

1 s.d.: single dose; 2 i.v.: intravenous; 3 i.g.: intragastrically; 4 i.s.: intubation in the stomach; 5 ”ad libitum” diet; 6 d.i.: duodenal infusion; 7 F: fucoxanthin, FxOH: fucoxanthinol, AxA: Amarouciaxanthin A.; 8 Detected in lymph but not in plasma.