Table 4.
Association of diet quality and food group and nutrient intake with inflammation, oxidative stress and blood pressure in youth with type 1 diabetes 1.
Dietary Components | CRP 2 (mg/L) | 8-iso-PGF2α (ng/mL) | SBP (mmHg) | DBP (mmHg) | ||||
---|---|---|---|---|---|---|---|---|
β ± SE | p | β ± SE | p | β ± SE | p | β ± SE | p | |
HEI-2015 | 0.0002 ± 0.002 | 0.90 | 0.002 ± 0.007 | 0.77 | 0.01 ± 0.02 | 0.59 | 0.01 ± 0.02 | 0.53 |
Total fruits 3 | 0.04 ± 0.06 | 0.46 | −0.23 ± 0.22 | 0.31 | −0.25 ± 0.71 | 0.73 | 0.10 ± 0.66 | 0.88 |
Whole fruits 3 | 0.07 ± 0.08 | 0.39 | −0.17 ± 0.28 | 0.54 | −0.73 ± 0.86 | 0.40 | −0.11 ± 0.88 | 0.90 |
Total vegetables 3 | −0.02 ± 0.05 | 0.67 | 0.06 ± 0.21 | 0.77 | −0.02 ± 0.69 | 0.97 | 0.69 ± 0.63 | 0.28 |
Dark green vegetables 3 | −0.04 ± 0.12 | 0.72 | −0.42 ± 0.50 | 0.40 | −0.52 ± 1.46 | 0.72 | −1.10 ± 1.38 | 0.42 |
Beans 3 | −0.30 ± 0.21 | 0.15 | 0.85 ± 1.05 | 0.42 | −0.64 ± 2.67 | 0.81 | −0.93 ± 2.43 | 0.70 |
Whole grains 3 | 0.04 ± 0.04 | 0.26 | −0.09 ± 0.16 | 0.60 | 0.03 ± 0.47 | 0.96 | −0.98 ± 0.46 | 0.04 |
Dairy 3 | −0.004 ± 0.07 | 0.95 | −0.47 ± 0.27 | 0.08 | 0.89 ± 0.81 | 0.27 | −0.99 ± 0.73 | 0.18 |
Protein foods 3 | −0.01 ± 0.02 | 0.55 | 0.09 ± 0.07 | 0.22 | −0.11 ± 0.20 | 0.59 | 0.20 ± 0.17 | 0.23 |
Seafood 3 | 0.02 ± 0.05 | 0.65 | −0.09 ± 0.21 | 0.69 | −0.18 ± 0.63 | 0.78 | 0.78 ± 0.61 | 0.20 |
Nuts and seeds 3 | 0.02 ± 0.04 | 0.61 | 0.25 ± 0.14 | 0.08 | 0.29 ± 0.45 | 0.53 | 0.21 ± 0.43 | 0.62 |
Refined grains 3 | −0.02 ± 0.02 | 0.42 | −0.18 ± 0.08 | 0.04 | 0.05 ± 0.25 | 0.85 | 0.04 ± 0.23 | 0.86 |
Sodium 4 | 0.02 ± 0.06 | 0.79 | −0.42 ± 0.27 | 0.12 | −0.53 ± 0.78 | 0.50 | 0.19 ± 0.78 | 0.80 |
Added sugars, % kcal | −0.00003 ± 0.004 | 0.99 | 0.01 ± 0.02 | 0.58 | −0.04 ± 0.05 | 0.34 | −0.01 ± 0.04 | 0.89 |
Saturated fat, % kcal | 0.01 ± 0.007 | 0.43 | 0.02 ± 0.03 | 0.57 | 0.01 ± 0.08 | 0.87 | −0.12 ± 0.08 | 0.13 |
Fatty acid 5 | 0.02 ± 0.04 | 0.59 | 0.19 ± 0.15 | 0.20 | 0.19 ± 0.45 | 0.67 | 0.98 ± 0.42 | 0.02 |
CRP, C-reactive protein; 8-iso-PGF2α, 8-iso-prostaglandin F2α; SBP, systolic blood pressure; DBP, diastolic blood pressure; HEI-2015, healthy eating index-2015. 1 Models were controlled for baseline treatment assignment, sex, diabetes duration, time-varying age, body mass index, Tanner stage, insulin regimen, physical activity, use of cardiac medication and glycemic control (HbA1c); 2 log-transformed to meet the normality assumption; 3 expressed as total number of cup- or ounce-equivalents per 1000 kcal; 4 expressed as grams per 1000 kcal; 5 calculated as (polyunsaturated fat + monounsaturated fat)/saturated fat.