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. 2018 Oct 5;19(10):3034. doi: 10.3390/ijms19103034

Figure 2.

Figure 2

Effect of treatment with CoCl2, CrCl3, and CoCr particles on relative wound closure in MG63 and SaOs2 cells, measured using ibidi® silicone inserts in an in vitro wound healing assay over 48 h. (A) Representative images of MG63 cells. Summary of the wound healing assay results for (B) MG63 and (C) SaOs-2 cells. Data represent the mean of four independent experiments. Data were examined in the time course using ANOVA (MG63: Co2+ p < 0.0001, Cr3+ p < 0.05, CoCr particles not significant; SaOs-2: Co2+ p < 0.001, Cr3+ p < 0.01, CoCr particles p < 0.01). For comparison of paired samples of treated cells vs. untreated control the post-hoc Bonferroni test was used (* p < 0.05, ** p < 0.01, *** p < 0.001).