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. 2018 Oct 5;19(10):3034. doi: 10.3390/ijms19103034

Table 1.

Genes down-regulated by CoCl2 after 24 h by at least a factor of 2 (normalization of Ct-values to glyceraldehyde 3-phosphate dehydrogenase (GAPDH)). The significance level was adjusted for multiple testing to 0.0006 (bold p-values are significant). A = in either the control or the test sample, the average Ct is high (>30 cycles).

Gene Symbol Fold Regulation Comments p-Value
BGN −2.12 3.45254 × 10−5
BMP4 −2.81 3.30439 × 10−5
BMP5 −21.52 A 1.83701 × 10−5
BMPR2 −2.15 0.003576291
CDH11 −4.14 7.55543 × 10−7
CHRD −2.22 0.025290803
COL14A1 −6.54 0.000723157
COL15A1 −6.74 A 4.58304 × 10−7
COL1A1 −2.52 0.000370615
COL1A2 −3.23 7.20666 × 10−6
COL3A1 −10.78 1.96377 × 10−5
COL5A1 −2.03 0.000462367
COMP −2.65 0.000687369
IGF1R −2.85 0.001021934
ITGA1 −2.13 0.037993599
ITGA3 −2.12 0.018352525
MMP2 −2.7 6.30662 × 10−7
RUNX2 −2.51 3.16733 × 10−6
SMAD1 −2.93 1.23015 × 10−5
SMAD2 −2.06 0.002343501
SOX9 −3.18 2.62519 × 10−6
TGFB2 −7.4 A 4.4503 × 10−7
TGFB3 −2.27 8.28135 × 10−5
TWIST1 −2.32 0.00077027
VEGFB −2.1 0.002973727