Table 3.
Genes down-regulated after 24 h of stimulation with particles by at least a factor of 2 (normalization of Ct-values to GAPDH). The significance level was adjusted for multiple testing to 0.0006 (bold p-values are significant), A = in either the control or the test sample, the average Ct is high (>30 cycles).
| Gene Symbol | Fold Regulation | Comments | p-Value |
|---|---|---|---|
| BMP5 | −2.16 | 0.0008533 | |
| BMP6 | −2.01 | 0.0209783 | |
| COL14A1 | −2.01 | 0.0197225 | |
| COL15A1 | −2.12 | A | 5.71 × 10−5 |
| PDGFA | −2.13 | 0.0004219 | |
| SMAD1 | −2.25 | 7.161 × 10−5 | |
| SMAD4 | −2.18 | 0.1233691 | |
| VDR | −2.08 | 0.0001971 |