Possible Applications of miRNA:
|
Predictors of response to therapy and prognostic biomarkers |
Use of miRNA as a drug—modulation of gene expression |
Prediction and detection of metastases or non-invasive tumor phenotypes |
Cancer diagnostics—detection of tumor specific miRNA signatures |
Advantages of Using miRNA:
|
Easy detection in various biological materials (serum/plasma, cerebrospinal fluid, faeces) |
High stability of miRNA molecules |
Ability to determine specific types of cancer, and predict response to therapy and prognosis based on miRNA expression profile |
Potential for use as antagonists in cancer therapy |