CCA |
Cholangiocarcinoma |
iCCA |
Intrahepatic Cholangiocarcinoma |
pCCA |
Perihilar Cholangiocarcinoma |
dCCA |
Distal Cholangiocarcinoma |
eCCA |
Extrahepatic Cholangiocarcinoma |
HCC |
Hepatocellular Carcinoma |
TME |
Tumor Microenvironment |
TAMs |
tumor-associated macrophages |
CTLA4 |
Cytotoxic T Lymphocyte Antigen-4 |
MHC |
Major Histocompatibility Complex |
GFAP |
Glial Fibrillary Acidic Protein |
CM |
Conditioned Medium |
CAFs |
Cancer Associated Fibroblasts |
HSCs |
Hepatic Stellate Cells |
HGF |
Hepatocyte Growth Factor |
AngII |
AngiotensinII |
EGFR |
Epidermal Growth Factor Receptor |
HB-EGF |
Heparin-Binding Epidermal Growth Factor |
TLR4 |
Toll-Like Receptor 4 |
ECM |
Extracellular Matrix |
MMPs |
Matrix Metalloproteinases |
PSC |
Primary Sclerosing Cholangitis |
PDGF |
Platelet-Derived Growth Factor |
TGF-β |
Transforming Growth Factor-beta |
FGF |
Fibroblast Growth Factor |
HGF |
Hepatocyte Growth Factor |
GM-CSF |
Granulocyte-Macrophage Colony Stimulating Factor |
IGF-1 |
Insulin-like Growth Factor |
SDF-1 |
Stromal derived factor-1 |
Hh |
Hedgehog |
CsLysoPLA |
Clonorchis sinensis Lysophospholipase |
TNF-α |
Tumor Necrosis Factor |
PD-1 |
Programmed Death 1 |
PD-L1 |
Programmed Death Ligand 1 |
VEGF |
Vascular Endothelial Growth Factor |