Figure 4.

Sorbitol-induced hemolysis is modulated by the TSPO ligands in infected red blood cells. Infected RBCs at 2 to 5 % parasitemia were washed three times in a culture medium, without serum, and resuspended at 50% hematocrit in a media containing 10 μM (A) or 50 μM (B) TSPO ligands. Hemolysis was quantified at several time-points, by absorption at 540 nm wavelength. Data are presented as mean ± SEM; N = 4. Differences between each ligand and control condition (vehicle) were considered significant when p < 0.01.