Figure 5.

JMV2959 and saline effects on active lever-pressing during methamphetamine IVSA in single rats in percentage of baseline mean (mean of last three baselines before pretreatment). JMV2959 3 mg/kg and saline were administered i.p. 20 min before the session. The effects are illustrated as follows: saline (open circle), JMV2959 (filled circle). The dotted line shows the baseline mean level (100%; “bas”). During the relapse-like behavior testing session (“rel”), the rats were not connected to the infusion pump.