Table 3.

ACE IC₅₀ of the size exclusion chromatographic fractions obtained from PN-1 after digestion by gastrointestinal proteases.

Fraction	Molecular Weight (Da)	Inhibition (%)	Peptide Content (mg/mL)	IER 1 (%/mg/mL)	IC50 (mg/mL)
A	1400–1180	74.0	0.210	350	— 2
B	1180–910	30.6	0.027	1130	0.0450
C	910–740	58.2	0.025	2230	0.0187
D	680–590	48.0	0.064	750	—
E	460–370	73.2	0.057	1280	0.0160
F	340–270	68.6	0.034	2020	0.0150
G	200–250	40.0	0.053	760	—

Each value represents the average of three samples. ¹ IER: inhibitory efficiency ratio = % inhibition/peptide content. ² Undetected.