Skip to main content
. 2018 Oct 9;19(10):3078. doi: 10.3390/ijms19103078

Figure 7.

Figure 7

Three-mon post-12C irradiation, there were fewer DG GCL BrdU+ cells in IRR mice relative to Sham mice. (A) Representative photomicrograph of BrdU staining in a Long-Term Sham mouse (mouse #13853; 400×, scale bar = 25 µm). (B) An unpaired t-test revealed fewer BrdU+ cells in IRR mice versus Sham mice (** p < 0.01; N = 4 Sham, N = 8 IRR). (C) An unpaired t-test revealed similar number of BrdU+ clusters in IRR and Sham mice (p > 0.05). (D) Bregma analysis of BrdU+ cells through two-way ANOVA (Bregma × Treatment) revealed a main effect of Treatment (F1,10 = 14.31; ** p < 0.01) and Bregma (F11,110 = 5.964; **** p < 0.0001), but no significant interaction (F11,110 = 1.775; p > 0.05). Post-hoc (Sidak’s multiple comparison) test revealed fewer BrdU+ cells at bregma positions −1.54 (a p < 0.05), −1.81 (a’ p < 0.01), and −2.08 (a p < 0.05) in IRR mice relative to Sham mice. Error bars ± SEM.