Figure 8.
Three-mon post-12C irradiation, DCX+ cell number was similar between IRR and Sham mice. (A) Representative photomicrograph of DCX staining in a Long-Term Sham mouse (mouse #13851; 400×, scale bar = 25 µm). (B) An unpaired t-test revealed no difference in DCX+ cells between IRR and Sham mice (p > 0.05; N = 4 Sham, N = 7 IRR). (C) Bregma analysis of DCX+ cells through two-way ANOVA (Bregma × Treatment) revealed a main effect of Bregma (F11,99 = 9.038; **** p < 0.0001), but not Treatment (F1,9 = 1.773; p > 0.05) and a significant interaction (F11,99 = 2.178; p < 0.05). Post-hoc (Sidak’s multiple comparison) revealed fewer DCX+ cells at bregma −3.43 (a p < 0.05). Error bars ± SEM.