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. 2018 Oct 5;19(10):3037. doi: 10.3390/ijms19103037

Figure 6.

Figure 6

Knockdown of LXRα inhibits intramuscular adipogenesis trough downregulation of Cebpβ and Klf8: (A) the LXRα binding DNA motif; (B) the LXRα binding sites prediction at the promoters of Cebpβ and Klf8, blue circles represent the LXRα binding sites, gray boxes represent exons; (C) the Cebpβ and Klf8 expression trend during intramuscular adipogenesis (n = 4); and (D,E) the mRNA levels of Cebpβ and Klf8 in LXRα-siRNA treated cells (n = 6). Data are shown as the means ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001, compared to that of negative control (NC).