Figure 3.

Low-dose synthetic ABA improves metabolic parameters in mice fed a high-glucose diet. Seven-week-old male CD1 mice (nine/group) were fed for 4 months a high-glucose diet containing 1 g/Kg BW glucose (administered with the drinking water) without (controls) or with ABA at approximately 1 µg/Kg BW. At the end of the study, fasting HbA1c, lipidemia, and body weight were measured and an OGTT was performed. (a) AUC of glycemia after OGTT, (b) HbA1c, (c) lipidemia, (d) body weight. Mean ± SD values are shown. p values by unpaired, two-tailed t-test.