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. 2018 Oct 3;10(10):541. doi: 10.3390/v10100541

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Fetal and placental virus titers after infection with ZIKV-MY or ZIKV-Natal. IFNAR1^−/− C57BL/6 pregnant mice were infected with ZIKV-MY or ZIKV-Natal at E12.5 and were euthanized at E17.5 of gestation. (a) Fetal heads, (b) placenta, and (c) deformed fetal–placental masses were collected, and tissue viral titers determined by the CCID₅₀ assay. *—p = 0.002; **—p = 0.045.