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LPS up-regulated interleukin (IL)-1β, IL-17, and tumor necrosis factor (TNF)-α concentration significantly in WT littermates. These changes were markedly attenuated in Fat-1 mice. (A) IL-1β; (B) IL-17; (C) TNF-α. ** p < 0.01, *** p < 0.001vs. WT/saline; # p < 0.05, ### p < 0.001 vs. WT/LPS. LPS: lipopolysaccharides; WT: Wild-type.
