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. 2018 Sep 21;10(10):1351. doi: 10.3390/nu10101351

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Figure 9. — LPS significantly up-regulated the protein expression of CD11b, GFAP, p75, and pro-BDNF, but down-regulated protein expression of BDNF and Trk B in the animal model. The protein expression of GFAP was increased in Fat-1 mice when compared with wild-type mice. The rise in the protein expression of CD11b and p75 was prevented, and there was an up-regulation of BDNF level at the same time in Fat-1 mice. (A) CD11b; (B) GFAP; (C) pro-BDNF; (D) BDNF; (E) Trk B; (F) p75. * p < 0.05, ** p < 0.01 vs. WT/saline; ^# p < 0.05 vs. WT/LPS; ^&& p < 0.01 vs. Fat-1/saline. LPS: lipopolysaccharides; WT: Wild-type. S: saline.