Figure 1.
Polyamine synthesis, degradation, and transport. T-bar indicates the inhibitory activity. Arrow indicates the metabolic pathway or flow of substances. Dashed arrow indicates the supply of aminopropyl group from dcSAM. ODC: ornithine decarboxylase; SSAT: spermidine/spermine N1-acetyltransferase; APAO: N1-acetylpolyamine oxidase.