Table 5.
IL-8 plasma levels and periodontal bacteria in a subgroup of 140 individuals.
| Bacteria (%) | IL-8 Levels, Median [IQR] in pg/mL | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Non-Periodontitis HC N = 19 |
HC+CP N = 41 |
T1DM+CP N = 36 |
T2DM+CP N = 44 |
T2DM+CP Subgroups | ||||||||
| Well/Satisfactorily Controlled N = 17 |
Unsatisfactorily Controlled N = 27 |
|||||||||||
| F. n. neg | 0.0 | - | 2.4 | 46.40 [46.40–46.40] |
0.0 | - | 2.3 | 30.86 [30.86–30.86] |
0.0 | - | 3.7 | 30.86 [30.86–30.86] |
| F. n. pos | 100.0 | 10.21 [8.61–12.66] |
97.6 | 10.80 [6.43–14.83] |
100.0 | 15.09 [9.73–20.32] |
97.7 | 14.18 [11.43–23.13] |
100.0 | 15.36 [12.29–23.13] |
96.3 | 13.77 [11.43–16.54] |
| A. a. neg | 68.4 | 10.21 [8.61–12.50] |
48.8 | 7.80 [5.99–13.32] |
55.6 | 18.41 [10.38–24.41] |
38.6 | 13.49 [12.33–16.54] |
29.4 | 28.16 [12.87–30.99] |
44.4 | 13.33 [10.58–14.50] |
| A. a. pos | 31.6 | 10.14 [9.09–13.49] |
51.2 | 13.45 [8.75–15.17] |
44.4 | 13.25 [8.63–17.72] |
61.4 | 15.09 [11.18–23.58] |
70.6 | 14.77 [10.52–18.48] |
55.6 | 15.09 [12.00–26.14] |
| P. g. neg | 68.4 | 9.73 [7.24–12.66] |
14.6 | 13.18 [7.99–27.35] |
25.0 | 24.33 [16.86–24.78] |
22.7 | 14.26 [12.33–26.14] |
17.6 | 12.33 [9.09–15.36] |
25.9 | 16.24 [12.50–30.86] |
| P. g. pos | 31.6 | 10.54 [9.41–12.50] |
85.4 | 10.57 [6.02–14.48] |
75.0 | 12.00 [7.24–18.92] * |
77.3 | 14.26 [11.43–23.13] |
82.4 | 16.36 [12.29–24.63] |
74.1 | 13.77 [10.58–15.82] |
| T. f. neg | 36.8 | 8.61 [6.72–9.73] |
2.4 | 46.40 [46.40–46.40] |
8.3 | 24.33 [19.67–40.67] |
0.0 | - | 0.0 | - | 0.0 | - |
| T. f. pos | 63.2 | 11.67 [9.81–13.66] * |
97.6 | 10.80 [6.43–14.83] |
91.7 | 13.33 [9.41–19.43] * |
100.0 | 14.26 [11.72–23.36] |
100.0 | 15.36 [12.29–23.13] |
100.0 | 14.04 [11.43–23.58] |
| T. d. neg | 47.4 | 8.77 [7.24–12.33] |
14.6 | 14.83 [13.45–19.37] |
25.0 | 20.87 [19.43–24.78] |
22.7 | 13.33 [12.50–15.36] |
17.6 | 12.87 [12.33–15.36] |
25.9 | 13.49 [12.50–16.54] |
| T. d. pos | 52.6 | 10.93 [9.41–13.83] |
85.4 | 10.15 [6.39–14.04] |
75.0 | 12.00 [7.24–18.57] * |
77.3 | 14.50 [11.18–23.91] |
82.4 | 16.36 [11.18–24.63] |
74.1 | 14.19 [10.58–23.75] |
| P. m. neg | 31.6 | 9.89 [7.24–12.66] |
2.4 | 46.40 [46.40–46.40] |
0.0 | - | 0.0 | - | 0.0 | - | 0.0 | - |
| P. m. pos | 68.4 | 10.21 [9.09–12.50] |
97.6 | 10.80 [6.43–14.83] |
100.0 | 15.09 [9.73–20.32] |
100.0 | 14.26 [11.72–23.36] |
100.0 | 15.36 [12.29–23.13] |
100.0 | 14.04 [11.43–23.58] |
| P. i. neg | 47.4 | 8.77 [6.72–12.66] |
41.5 | 7.99 [6.02–14.48] |
41.7 | 17.89 [12.15–24.33] |
45.5 | 14.08 [10.14–16.39] |
35.3 | 11.76 [9.09–15.36] |
51.9 | 15.05 [11.43–23.58] |
| P. i. pos | 52.6 | 10.54 [9.41–12.50] |
58.5 | 11.57 [7.60–15.19] |
58.3 | 12.00 [7.84–18.92] |
54.5 | 14.26 [12.40–24.27] |
64.7 | 20.27 [12.87–28.16] * |
48.1 | 13.49 [12.00–14.67] |
Neg: negative; pos: positive. * P < 0.05 in comparison of IL-8 plasma levels between patients negative and positive for the specific bacteria (Pcorr > 0.05).