Table 1.
Summary of studies included in review
| Study | Setting | Number of patients with stoma | Mean age in years (range) | Male-to-female ratio | Indication for stoma | Mean time to stoma closure / end of follow-up (range) |
| Chude, 200817 | Surgical unit, Greece | LI 136 | 55.5 (22–89) | 76:60 | CRC | – |
| Dong, 201218 | Surgical unit, China | EC 62 | 57.9 (SD: 10.3) | 33:29 | CRC | F 6–60 months |
| Edwards, 200119 | Surgical unit, UK | LI 34 LC 36 |
LI 63* (40–85) LC 68* (32–90) |
LI 27:7 LC 2:14 |
CRC | C LI 62* (17–120) days C LC 73* (28–141) days |
| Fleshman, 201420 | University hospitals, US | EI 23** EC 35** |
59.1 (SD: 14.4) | 29:29 | CRC, IBD, other | F 2 years |
| Gonzalez, 200021 | Surgical unit, US | LI 9** LC 78** |
26.4 | All patients 168:8 | Other | – |
| Gooszen, 199822 | 5 Surgical units, Netherlands | LI 37 LC 39 |
LI 63.2 (26–86) LC 64.7 (29–83) |
LI 14:23 LC 13:26 |
CRC, DD, other | – |
| Hardt, 201623 | University hospital, Germany | LI 30 | 50 (19–79) | 19:11 | CRC, IBD, other | F 112 (15–642) days |
| Jänes, 200924 | Surgical unit, Sweden | EC 27 | 71 | 16:11 | CRC, DD, IBD, other | F 5 years |
| Law, 200225 | University hospital, Hong Kong | LI 42 LC 38 |
LI 65.2 LC 67.8 (all patients 38–87) |
LI 26:16 LC 23:15 |
CRC | C LI 183* days C LC 180* days |
| López-Cano, 201226 | University hospital, Spain | EC 17 | 65.9 (SD: 13.9) | 7:10 | CRC | F 317* days |
| Patil, 201227 | University hospital, India | LI 30 | All patients 32.6 (16–63) | 22:8 | Other | F 6 months |
| Roed-Petersen, 199228 | University hospital, Denmark | EC 51 | 71* (38–87) | 30:21 | - | – |
| Salum, 200629 | 15 Surgical units, US | LI 64 | 41.5 (20–84) | 38:26 | - | – |
| Serra-Aracil, 200930 | Surgical unit, Spain | EC 27 | 67.2 (SD: 9.7) | – | CRC | F 29* (13–49) months |
| Speirs, 200631 | Surgical unit, UK | LI 29** | 63 (IQR: 52–70) | – | CRC, other | F 3 months |
| Tang, 200332 | University hospital, Singapore | Phase I: LI 54 Phase II: LI 36 |
Phase I: 62.5* (24–81) Phase II: 68* (37–85) |
Phase I: 33:21 Phase II: 16:20 |
CRC, DD, other | F Phase I: 22* (0.2–45.5) months F Phase II: 6.9* (0.2–37) months |
| Thoker, 201433 | University hospital, India | LI 34 | – | – | CRC | F 6 months |
| Vierimaa, 201534 | 5 Surgical units, Finland | EC 41 | 65.1 (SD: 11.7) | 19:16 | CRC | F 12 months |
C = time to stoma closure; CRC = colorectal cancer; DD = diverticular disease; EC = end colostomy; EI = end ileostomy; F = time to end of follow-up; IBD = inflammatory bowel disease; IQR = interquartile range; LC = loop colostomy; LI = loop ileostomy; SD = standard deviation
*Median
**Not intention-to-treat population