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. 2018 Oct 20;19(10):3253. doi: 10.3390/ijms19103253

Figure 3.

Figure 3

Concentration of metallothionein (MT) in MCF-7 cells treated by DOX, C60 and C60–DOX complexes. Concentration of MT-1/2 in MCF-7 cells treated by (A) DOX, (B) C60, (C) complexes of C60–DOX. For other experimental conditions, see Material and Methods. a p < 0.05 when compared to control cells; b p < 0.05 when compared to cells treated by 1 µM DOX; c p < 0.05 when compared to cells treated by 25 mg/mL C60; d p < 0.05 when compared to cells treated by C60–DOX complexes (25 mg/mL C60-1 µM DOX and 50 mg/mL C60-2 µM DOX).