Table 4.
Clinical trials with BM-HSCs for cardiac regeneration.
| Reference | Clinical Trial | Disease | Delivery Method | Subjects | LVEF Improvement |
|---|---|---|---|---|---|
| Stamm [78] | Phase I | ICM | IM | Treated: 35 Control: 20 |
Yes |
| Tendera [85] | REGENT | AMI | IC | Treated: 16 0Control: 40 |
No |
| Povsic [86] | RENEW | RA | IM | Treated: 57 Control: 55 |
Not shown |
| Noiseux [87] | IMPACT-CABG | ICM | IM | Treated: 2 0Control: 20 |
Not shown |
| Quyyum [88] | PreSERVE-AMI | AMI | IC | Treated: 78 Control: 83 |
Yes |
ICM: ischemic cardiomyopathy; IM: intramyocardial injection; AMI: acute myocardial infarction; IC: intracoronary infusion; RA: refractory angina.