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. 2018 Nov 2;13:40. doi: 10.1186/s40248-018-0152-5

Table 4.

Percentage of responders in the clinical evaluation of cefditoren efficacy in clinical trials. Published data

References Cefditoren 200 mg bid Cefditoren 400 mg bid Comparatorsa
EOTb EFc EOTb EFc EOTb EFc
Pharyngotonsillitis 90-92 93.4 – 98.6 88.9–99.2 88.6–97.1 84.4–100
Rhinosinusitis 90,93 81.3–95.2 63.6–91.0 76.5–83.1 70.2–71.9 75.5–97.7 66.2–95.1
AECBd 89,94–97 80–88.8 79.7–83.0 84.4–95.5 78.1–85.6 75.0–98.9 79.8–85.7
CAPe 89,98,99 87.2 – 91.8 88.4–87.8 89.2–90.1 83.7–87.2 90.3–92.2 87.8–93.8

aPenicillin V or VK (90–92) for pharyngotonsillitis, amoxicillin/clavulanic acid (90,93) or cefuroxime (90) for rhinosinusitis, cefuroxime (89,94,96) or clarithromycin (89,95) for AECB, and amoxicillin/clavulanic acid (89,98), and cefpodoxime (89,99) for CAP

bEOT = End of Treatment

cEF = End of Follow up

dAECB = Acute exacerbation of chronic bronchitis

eCAP = Community-acquired pneumonia