Table 4.
References | Cefditoren 200 mg bid | Cefditoren 400 mg bid | Comparatorsa | ||||
---|---|---|---|---|---|---|---|
EOTb | EFc | EOTb | EFc | EOTb | EFc | ||
Pharyngotonsillitis | 90-92 | 93.4 – 98.6 | 88.9–99.2 | – | – | 88.6–97.1 | 84.4–100 |
Rhinosinusitis | 90,93 | 81.3–95.2 | 63.6–91.0 | 76.5–83.1 | 70.2–71.9 | 75.5–97.7 | 66.2–95.1 |
AECBd | 89,94–97 | 80–88.8 | 79.7–83.0 | 84.4–95.5 | 78.1–85.6 | 75.0–98.9 | 79.8–85.7 |
CAPe | 89,98,99 | 87.2 – 91.8 | 88.4–87.8 | 89.2–90.1 | 83.7–87.2 | 90.3–92.2 | 87.8–93.8 |
aPenicillin V or VK (90–92) for pharyngotonsillitis, amoxicillin/clavulanic acid (90,93) or cefuroxime (90) for rhinosinusitis, cefuroxime (89,94,96) or clarithromycin (89,95) for AECB, and amoxicillin/clavulanic acid (89,98), and cefpodoxime (89,99) for CAP
bEOT = End of Treatment
cEF = End of Follow up
dAECB = Acute exacerbation of chronic bronchitis
eCAP = Community-acquired pneumonia