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Deleting one Bdnf allele does not prevent the later loss of islet sympathetic nerves induced by viral injection in RIP-GP mice. In Bdnf+/− mice there is a marked loss of islet sympathetic nerves after 3 weeks of LCMV-induced diabetes that is identical to that seen in Bdnf wild-type mice (Bdnf+/+). NPY, Neuropeptide tyrosine. *p<0.05 vs vehicle (Veh)-treated control
