Table 1.

Expression of immune effector molecules detected by flow cytometry (mean±SD,%)

Effector cell molecule	DC-rAAV/AFP	Dex	DC-Dex	Non-transfected DCs
CD45RO	35.46±1.56a,b	32.24±4.58a,b	53.83±3.05a	24.96±0.53
CD45RA	40.46±7.94a,b	32.63±0.95a	27.8±3.3a	54.33±2.9
CD11a/CD244	56±2.49a,b	50.93±3.41a,b	70.06±3.49a	42.86±6.01
CD28	49.3±1.15	49.83±3.22	56.1±2.87a	43.96±0.98
OX40	15.79±3.86	21.47±7.66	28.06±2.67a	10.35±3.25
HLA-DR	53.83±3.53	55.16±3.78	59.36±5.78a	52.56±4.71
CD69	4.08±0.61	5.3±1.31	7.06±0.86	4.53±1.55
CD71	63.9±3.98	61.26±4.99	64.53±6.84	57.26±4.84
CD95	52.3±3.28	54.61±2.74	55.95±4.62	48.86±3.12
PD-1	8.69±1.21b	13.94±2.11	17.67±2.4a	8.63±1.48
CTLA-4	1.26±0.06	1.27±0.17	1.4±0.28	1.38±0.05
CD8/GrB	53.56±1.67a,b	57.36±1.35a	61.5±1.17a	43.36±2.48
CD8/perforin	31.96±1.79a,b	32.2±0.46a,b	37.6±1.53a	19.46±1.47

Notes:

^aP<0.05 vs non-transfected DCs;

^bP<0.05 vs DC-Dex.

Abbreviations: AFP, alpha-fetoprotein; DC, dendritic cell; Dex, dendritic cell-derived xosome; rAAV, recombinant adeno-associated viral vector.