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| Phenotypes Observed in Global AHR-KO mice |
| Increased numbers of peripheral white blood cells |
| Alterations in white blood cell subsets |
| Elevated HSC oxidative stress elevated |
| HSC DNA damage increased |
| HSC p16 expression decreased |
| Spleen weight increased |
| Decreased HSC self-renewal during serial transplants |
| 672 genes altered compared to WT using microarray |
