Table 3. Patients without direct treatment for TMA, features and outcomes.
| Patient # | MDT period | Age (years) |
Sex | Etiology | Reason for no treatment | Recommended treatment | Outcome |
|---|---|---|---|---|---|---|---|
| 1 | Pre | 10 | M | aHUS, genetic variants of C3 and CFH. | Diarrhea, mild renal dysfunction and rapid renal restauration. | Intravenous fluids. | Normal renal function. |
| 2 | Pre | 40 | F | Pregnancy-HUS. | Mild renal disfunction, low platelets. | Immediate delivery. | Normal renal function, stroke sequelae. Left leg paresis, convulsions. |
| 3 | Pre | 18 | M | Drug related HUS. CNI-BMT. | Mild renal dysfunction, anemia and thrombocytopenia. | Stop CNI. | Normal renal function. |
| 4 | Pre | 27 | M | Urinary infection related-HUS. | Unsuspected TMA. Sepsis suspicion. | Intravenous fluids, antibiotics. | Dead in lower than 20 hours. |
| 5 | Post | 57 | M | Urologic disseminate malignancy. | Futile treatment. | Comfort. | Dead. |
| 6 | Post | 59 | M | Refractory hematologic malignancy. | Futile treatment. | Comfort. | Dead |
aHUS: atypical hemolytic uremic syndrome, BMT: bone marrow transplant, CFH: complement factor H, CNI: calcineurin inhibitor, MDT: multidisciplinary team.