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. 2018 Nov 2;13(11):e0206928. doi: 10.1371/journal.pone.0206928

Table 4. Birth outcome of off springs of different heterozygous thalassaemia conditions.

Parameter Significance (compared to controls)
Birth weight (g) Mean ± SD
Control group (n = 102) 3043 ± 479
β-thalassaemia trait (n = 12) 3210 ± 639 t = 1.06, p = 0.27
α+- thalassaemia trait (α-/αα) (n = 28) 2795 ± 503 t = 2.39, p<0.05
Co-inheritance of α- and β-thalassaemia (n = 3) 3183 ± 350 t = 0.498, p = 0.61
Low birth weight (<2500g) N, prevalence(%)
Control group (n = 102) 10 (9.8%)
β-thalassaemia trait (n = 12) 1 (8.3%) p = 1.0
α+- thalassaemia trait (α-/αα) (n = 28) 7 (25.0%) p = 0.054
Co-inheritance of α- and β-thalassaemia (n = 3) 0 (0%) p = 1.0
Prematurity (<37 weeks gestation) N, prevalence(%)
Control group (n = 102) 6 (5.9%)
β-thalassaemia trait (n = 12) 0 (0%) p = 1.0
α+- thalassaemia trait (α-/αα) (n = 28) 7 (25.0%) p<0.01
Co-inheritance of α- and β-thalassaemia (n = 3) 0 (0.0%) p = 1.0