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(A) Representative flow cytometry histograms of cell cycle analysis of A549 cells after incubation with various formulations of DOX for 24 h. (B) The percentages of apoptotic A549 cells after incubation with various formulations of DOX for 24 h. RGDfC-Se@DOX, selenium nanoparticles conjugated with RGDfC and DOX; Se@ DOX, selenium nanoparticles conjugated with DOX.
Abbreviations: DOX, doxorubicin; FITC, fluorescein isothiocyanate; PI, propidium iodine; RGDfC, Arg–Gly–Asp–d-Phe–Cys.
