Figure 5.

T-cell IFN-γ enzyme-linked immunospot responses following DNA priming (week 20) and protein boost (week 22), the primary endpoint (A). All responses expressed as spot-forming units (SFU) per million peripheral blood mononuclear cells (PBMC), with background subtracted (SFU/10⁶ PBMC). Mean values ±95% confidence intervals are shown. Shading represents responses to the three peptide pools (PP). Antigen-specific CD4 (B) and CD8 (C) T cells producing IFN-γ at week 20 and week 22 as measured by ICS. The boxes show the median ± interquartile ranges and min/max values. Statistical analysis was performed using a Kruskal–Wallis Test with Dunn's correction for multiple comparisons. Color images available online at www.liebertpub.com/hum