Table 3. Genotype and allele frequencies of TLR6 gene polymorphism in Saudi BC cases and controls.
| SNP ID | Genotype | Cases | Controls | OR | (95% CI) | χ2 –Value | P*- Value |
|---|---|---|---|---|---|---|---|
| n = 125 | n = 110 | ||||||
| Val/Val | 117 (0.94) | 102 (0.93) | Ref | ||||
| rs3796508 | Val/Met | 8 (0.06) | 7 (0.06) | 0.996 | 0.349–2.843 | 0.0009 | 0.99453 |
| Met/Met | 0 (0.00) | 1 (0.01) | 0.291 | 0.012–7.216 | 1.14 | 0.28542 | |
| Val/Met +Met/Met | 8 (0.06) | 8 (0.07) | 0.872 | 0.316–2.406 | 0.07 | 0.79099 | |
| Val | 242 (0.97) | 211 (0.96) | Ref | ||||
| Met | 8 (0.03) | 9 (0.04) | 0.775 | 0.294–2.045 | 0.27 | 0.60574 | |
| n = 127 | n = 120 | ||||||
| Ser/Ser | 0 (0.00) | 0 (0.00) | Ref | ||||
| rs5743810 | Ser/Pro | 36 (0.28) | 4 (0.03) | 8.111 | 0.14–461.1 | — | 1 |
| Pro/Pro | 91 (0.72) | 116 (0.97) | 0.785 | 0.015–39.962 | — | 1 | |
| Ser/Pro +Pro/Pro | 127 (1) | 120 (1) | 1.058 | 0.021–53.747 | — | 1 | |
| Ser | 36 (0.14) | 4 (0.02) | Ref | ||||
| Pro | 218 (0.86) | 236 (0.98) | 0.103 | 0.036–0.293 | 25.94 | <0.00001* |
* p <0.05