Table 4. Genotype and allele frequencies of TLR6 SNPs in Saudi BC cases versus controls based on age of diagnostic.

SNP ID	Genotype	Cases	Controls	OR	(95% CI)	χ2 Value	P*- Value
patient’s age ≤ 48 years
rs3796508		n = 44	n = 56
	Val/Val	40(0.91)	55(0.98)	Ref
	Val/Met	4(0.09)	1(0.02)	5.500	0.592–51.090	2.77	0.09615
	Met/Met	0(0.00)	0(0.00)	1.370	0.027–70.519	—	1
	Val/Met +Met/Met	4(0.09)	1(0.02)	5.500	0.592–51.090	2.77	09615
	Val	84(0.95)	111(0.99)	Ref
	Met	4(0.05)	1(0.01)	5.286	0.580–48.162	2.70	0.18404
rs5743810		n = 45	n = 55
	Ser/Ser	0(0.00)	0(0.00)	Ref
	Ser/Pro	14(0.31)	2(0.04)	5.800	0.092–365.479	—	1
	Pro/Pro	31(0.69)	53(0.96)	0.589	0.011–30.413	—	1
	Ser/Pro+Pro/Pro	45(1)	55(1)	0.820	0.016–42.132	—	1
	Ser	14(0.16)	2(0.02)	Ref
	Pro	76(0.84)	108(0.98)	0.101	0.022–0.455	12.69	0.00037*
SNP ID	Genotype	Cases	Controls	OR	(95% CI)	χ2 Value	P*- Value
patient’s age > 48 years
rs3796508		n = 81	n = 54
	Val/Val	77 (0.95)	47 (0.87)	Ref
	Val/Met	4 (0.05)	6 (0.11)	0.407	0.109–1.517	1.89	0.16922
	Met/Met	0 (0.00)	1 (0.02)	0.204	0.008–5.118	1.62	0.20350
	Val/Met +Met/Met	4 (0.05)	7 (0.13)	0.349	0.097–1.256	2.79	0.09499
	Val	158 (0.98)	100 (0.93)	Ref
	Met	4 (0.02)	8 (0.07)	0.316	0.093–1.078	3.72	0.07084
rs5743810		n = 82	n = 55
	Ser/Ser	0 (0.00)	0 (0.00)	Ref
	Ser/Pro	22 (0.27)	2 (0.04)	9.000	0.144–560.703	—	1
	Pro/Pro	60 (0.73)	53 (0.96)	1.131	0.022–57.981	—	1
	Ser/Pro+Pro/Pro	82 (1)	55 (1)	1.486	0.029–76.027	—	1
	Ser	22 (0.13)	2 (0.02)	Ref
	Pro	142 (0.87)	108 (0.98)	0.120	0.028–0.519	11.08	0.00087*

* = P<0.05, Ref = Reference allele