Table 5. Genotype and allele frequencies TLR6 SNPs in Saudi BC cases and controls based on ER+/ER^- status.

SNP ID	Genotype	Cases	Controls	OR	(95% CI)	χ2 Value	P*- Value
ER+
rs3796508		n = 75	n = 110
	Val/Val	71 (0.95)	102 (0.93)	Ref
	Val/Met	4 (0.05)	7 (0.06)	0.821	0.232–2.909	0.09	0.75954
	Met/Met	0 (0.00)	1 (0.01)	0.478	0.019–11.898	0.69	0.40504
	Val/Met +Met/Met	4 (0.05)	8 (0.07)	0.718	0.208–2.477	0.28	0.59899
	Val	146 (0.97)	211 (0.96)	Ref
	Met	4 (0.03)	9 (0.04)	0.642	0.194–2.125	0.53	0.46507
rs5743810		n = 76	n = 120
	Ser/Ser	0 (0.00)	0 (0.00)	Ref
	Ser/Pro	22 (0.29)	4 (0.03)	5.000	0.087–286.553	—	1
	Pro/Pro	54 (0.71)	116 (0.97)	0.468	0.009–23.889	—	1
	Ser/Pro+Pro/Pro	76 (1)	120 (1)	0.635	0.012–32.331	—	1
	Ser	22 (0.14)	4 (0.02)	Ref
	Pro	130 (0.86)	236 (0.98)	0.100	0.034–0.297	24.65	<0.00001*
SNP ID	Genotype	Cases	Controls	OR	(95% CI)	χ2 Value	P*- Value
ER-
rs3796508		n = 48	n = 110
	Val/Val	44 (0.92)	102 (0.93)	Ref
	Val/Met	4 (0.08)	7 (0.06)	1.325	0.369–4.756	0.19	0.66555
	Met/Met	0 (0.00)	1 (0.01)	0.768	0.031–19.214	0.43	0.51193
	Val/Met +Met/Met	4 (0.08)	8 (0.07)	1.159	0.332–4.051	0.05	0.81698
	Val	92 (0.96)	211 (0.96)	Ref
	Met	4 (0.04)	9 (0.04)	1.019	0.306–3.394	0.0009	1
rs5743810		n = 49	n = 120
	Ser/Ser	0 (0.00)	0 (0.00)	Ref
	Ser/Pro	14 (0.29)	4 (0.03)	3.222	0.056–186.825	—	1
	Pro/Pro	35 (0.71)	116 (0.97)	0.305	0.006–15.635	—	1
	Ser/Pro+Pro/Pro	49 (1)	120 (1)	0.411	0.008–20.993	—	1
	Ser	14 (0.14)	4 (0.02)	Ref
	Pro	84 (0.86)	236 (0.98)	0.102	0.033–0.318	21.98	<0.00001*

* = P<0.05, Ref = Reference allele