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. Author manuscript; available in PMC: 2019 Oct 12.
Published in final edited form as: Cancer. 2018 Oct 12;124(18):3742–3752. doi: 10.1002/cncr.31645

Figure 1: Association of SNPs with risk of osteosarcoma in an extended region of chromosome 19p13.11 previously associated with adult height attainment.

Figure 1:

Genotypes include both “on array” SNPs and additional SNPs imputed as described in the Methods. A recent GWAS of adult height attainment identified rs8103992 (purple diamond shape) as the lead SNP in this region23 and we used it as one of 416 SNPs comprising our polygenic height score. Other SNPs are displayed by color, showing their extent of genetic linkage with rs8103992. The SNP most significantly associated with risk of osteosarcoma, rs11878202, is located in an intron of GMIP. Recombination rate, genetic position, and the locations of nearby genes are indicated.