Table 3:
Binary logistic regressions for Black race versus overall prostate cancer and Gleason ≥3+4 prostate cancer diagnosis
| Multivariable Logistic Regression for Cancer on Biopsy vs. Negative Biopsy | Multivariable Logistic Regression for Gleason ≥3+4 Prostate Ca vs. Gleason 3+3/Negative Biopsy | |||||
|---|---|---|---|---|---|---|
| Covariates |
Odds Ratio (95% C.l.) |
p value |
Covariates |
Odds Ratio
(95% C.l.) |
p value |
|
| Black race |
2.13 (1.33–3.40) |
0.002 | Black race X Abnormal DRE |
2.93 (1.31–6.53) |
0.009 | |
| Abnormal DRE (yes) | 1.14 (0.74–1.76) |
0.57 | Black race X Normal DREa | 1.14 (0.56–2.32) |
0.72 | |
| - | - | - | Non-Black race X Abnormal DREa |
0.86 (0.39–1.94) |
0.72 | |
| - | - | - | Non-Black race X Normal DREa (ref) |
1 | - | |
| 1st degree Fam Hx (yes) |
1.74 (1.07–2.83) |
0.02 | 1st degree Fam Hx (yes) | 1.48 (0.86–2.56) |
0.16 | |
| Age, years |
1.04 (1.01–1.07) |
0.02 | Age, years |
1.05 (1.01–1.08) |
0.02 | |
| Log(PSA), ng/ml |
4.32 (2.29–8.14) |
<0.001 |
Log(PSA), ng/ml |
13.09 (6.06–28.27) |
<0.001 | |
| Publicly funded site (yes) |
0.53 (0.28–0.98) |
0.04 | Publicly funded site (yes) |
0.29 (0.14–0.60) |
0.001 | |
| High School completion (yes) | 1.17 (0.74–1.84) |
0.49 | High School completion (yes) | 0.84 (0.48–1.48) |
0.55 | |
| Prostate volume, cm3 |
0.98 (0.97–0.99) |
<0.001 | Prostate volume, cm3 |
0.98 (0.97–0.99) |
<0.001 | |
| 5-ARI use (yes, ≥6 months) |
0.38 (0.19–0.74) |
0.004 | 5-ARI use (yes, ≥6 months) |
0.32 (0.12–0.85) |
0.02 | |
| Married (yes) | 0.86 (0.56–1.33) |
0.81 | Married (yes) | 0.61 (0.36–1.03) |
0.06 | |
| Annual Income < $30K/year | 1.1 (0.67–1.78) |
0.72 | Annual Income < $30K/year | 1.15 (0.64–2.06) |
0.63 | |
Note: Bolded variables have a p-value < 0.05.